SB-611812

SB-611812
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay33247-1 1 mg -

6 - 10 business days*

67.00€
Cay33247-5 5 mg -

6 - 10 business days*

287.00€
 
SB-611812 is an antagonist of the urotensin II receptor (UTR). It binds to recombinant rat UTR... more
Product information "SB-611812"
SB-611812 is an antagonist of the urotensin II receptor (UTR). It binds to recombinant rat UTR (Ki = 121 nM) and inhibits contraction of isolated rat aorta induced by urotensin II (pA2 = 6.59) but not potassium chloride, endothelin-1, angiotensin II, or phenylephrine. SB-611812 (30 mg/kg) decreases myocardial interstitial fibrosis and the ratio of collagen I to collagen III in a rat model of ischemia induced by ligation of the left anterior descending (LAD) artery.Formal Name: 2,6-dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)-benzenesulfonamide. CAS Number: 345892-71-9. Molecular Formula: C17H16Cl3F3N2O3S. Formula Weight: 491.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 10 mM. SMILES: O=S(NC1=CC=C(C(OCCN(C)C)=C1)Cl)(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)=O. InChi Code: InChI=1S/C17H16Cl3F3N2O3S/c1-25(2)5-6-28-15-9-11(3-4-12(15)18)24-29(26,27)16-13(19)7-10(8-14(16)20)17(21,22)23/h3-4,7-9,24H,5-6H2,1-2H3. InChi Key: UIZHOFJFIOCYLH-UHFFFAOYSA-N.
Keywords: 2,6-dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)-benzenesulfonamide
Supplier: Cayman Chemical
Supplier-Nr: 33247

Properties

Application: Urotensin 2 receptor antagonist
MW: 491.7 D
Formula: C17H16Cl3F3N2O3S
Purity: >98%
Format: Solid

Database Information

CAS : 345892-71-9| Matching products
KEGG ID : K04241 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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