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Item number: Cay33247-1

SB-611812 is an antagonist of the urotensin II receptor (UTR). It binds to recombinant rat UTR (Ki = 121 nM) and inhibits contraction of isolated rat aorta induced by urotensin II (pA2 = 6.59) but not potassium chloride, endothelin-1, angiotensin II, or phenylephrine. SB-611812 (30 mg/kg) decreases myocardial...

Keywords:	2,6-dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)-benzenesulfonamide
Application:	Urotensin 2 receptor antagonist
CAS	345892-71-9
MW:	491.7 D

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