SB 525334
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SB-525334 is a potent and selective inhibitor of the TGF-beta1R and ALK5 (IC50: 14.3... more
Product information "SB 525334"
Description: SB-525334 is a potent and selective inhibitor of the TGF-beta1R and ALK5 (IC50: 14.3 nM). Target: ALK, TGF-beta/Smad. Smiles: C(C)(C)(C)C=1NC(=C(N1)C=2N=C(C)C=CC2)C3=CC4=C(C=C3)N=CC=N4. References: Grygielko ET, et al. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J Pharmacol Exp Ther. 2005 Jun,313(3):943-51.
| Keywords: | SB525334 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1763 |
Properties
| Application: | TGFBR1 inhibitor |
| MW: | 343.42 D |
| Formula: | C21H21N5 |
Database Information
| CAS : | 356559-20-1| Matching products |
| KEGG ID : | K04674 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H315, H319, H335, H413 |
| P Phrases: | P261, P264, P270, P271, P273, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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