SB-431542
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SB-431542 is an inhibitor of ALK5/TGF-beta type I Receptor (IC50=94 nM) and is... more
Product information "SB-431542"
Description: SB-431542 is an inhibitor of ALK5/TGF-beta type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells. Target: TGF-beta/Smad, ALK. Smiles: NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCOc2c1. References: Halder SK, et al. A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia. 2005 May,7(5):509-21.
| Keywords: | SB 431542 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1726 |
Properties
| Application: | Smad3 phosphorylation inhibitor, TGFBR1/ALK4/ALK7 kinase inhibitor |
| MW: | 384.39 D |
| Formula: | C22H16N4O3 |
Database Information
| CAS : | 301836-41-9| Matching products |
| KEGG ID : | K04674 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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