Saxitoxin
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay45566-500 | 500 µl | - |
5 - 10 business days* |
452.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Saxitoxin is a marine guanidinium toxin and voltage-gated sodium channel blocker (IC50 = 4.3 nM).... more
Product information "Saxitoxin"
Saxitoxin is a marine guanidinium toxin and voltage-gated sodium channel blocker (IC50 = 4.3 nM). It selectively binds to sodium channels in rat brain and skeletal muscle over rat heart homogenates (Kds = 0.114, 0.49, and 10 nM, respectively). Saxitoxin (3 and 10 µM) also inhibits L-type calcium channels in isolated mouse ventricular myocytes and tsA201 cells and human-ether-a-go-go (hERG), also known as Kv11.1, in HEK293 cells. It induces tachycardia, hypotension, myocardial failure, and cardiac arrest in anesthetized cats when administered intravenously at a dose of 10 µg/kg.. SMILES: OC1([C@](N(CC1)C(N)=N2)(NC(N)=N3)[C@]3([H])[C@@H]2COC(N)=O)O. InChi Code: InChI=1S/C10H17N7O4/c11-6-15-5-4(3-21-8(13)18)14-7(12)17-2-1-9(19,20)10(5,17)16-6/h4-5,19-20H,1-3H2,(H2,12,14)(H2,13,18)(H3,11,15,16)/t4-,5-,10-/m0/s1. InChi Key: RPQXVSUAYFXFJA-HGRQIUPRSA-N
| Keywords: | STX, (3aS,4R,10aS)-2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-1H,10H-pyrrolo[1,2-c]purine-10,10-diol |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 45566 |
Properties
| Application: | Marine guanidinium toxin, voltage-gated sodium channel blocker |
| MW: | 299.29 D |
| Formula: | C10H17N7O4 |
| Format: | Solution |
Database Information
| CAS : | 35523-89-8| Matching products |
| KEGG ID : | K04833 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H300, H310, H330 |
| P Phrases: | P260, P262, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P310, P320, P321, P330, P361+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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