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Item number: Cay45566-500

Saxitoxin is a marine guanidinium toxin and voltage-gated sodium channel blocker (IC50 = 4.3 nM). It selectively binds to sodium channels in rat brain and skeletal muscle over rat heart homogenates (Kds = 0.114, 0.49, and 10 nM, respectively). Saxitoxin (3 and 10 µM) also inhibits L-type calcium channels in isolated...

Keywords:	STX, (3aS,4R,10aS)-2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-1H,10H-pyrrolo[1,2-c]purine-10,10-diol
Application:	Marine guanidinium toxin, voltage-gated sodium channel blocker
CAS	35523-89-8
MW:	299.29 D

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