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Product information "(S)-(+)-Clopidogrel (sulfate)"
(S)-(+)-Clopidogrel is a prodrug form of the active metabolite of clopidogrel, which is a purinergic P2Y12 receptor antagonist. It inhibits aggregation of rat platelets induced by ADP, collagen, and thrombin ex vivo (ID50s = 4, 4.8, and 2.9 mg/kg). (S)-(+)-Clopidogrel increases tail bleeding time in rats in a dose-dependent manner. Formulations containing (S)-(+)-clopidogrel have been used in the treatment of acute coronary syndrome and peripheral artery disease and to reduce the reoccurrence of myocardial infarction and stroke.Formal Name: S-alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monosulfate. CAS Number: 120202-66-6. Synonyms: SR 25990C. Molecular Formula: C16H16ClNO2S . H2SO4. Formula Weight: 419.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml, DMSO: 10 mg/ml, Ethanol: 3 mg/ml. SMILES: ClC1=CC=CC=C1[C@@H](C(OC)=O)N2CCC(SC=C3)=C3C2.O=S(O)(O)=O. InChi Code: InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14,1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3,(H2,1,2,3,4)/t15-,/m0./s1. InChi Key: FDEODCTUSIWGLK-RSAXXLAASA-N.
Keywords:
SR 25990C, S-alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monosulfate
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