RepSox
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: RepSox (ALK5 Inhibitor II) is a TGFbetaR-1/ALK5 inhibitor that selectively inhibits... more
Product information "RepSox"
Description: RepSox (ALK5 Inhibitor II) is a TGFbetaR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM). RepSox induces adipogenesis in MEFs cells. Target: TGF-beta/Smad, ALK. Smiles: Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1. References: Tu WZ, et al. RepSox, a small molecule inhibitor of the TGFbeta receptor, induces brown adipogenesis and browning of white adipocytes. Acta Pharmacol Sin. 2019 Dec,40(12):1523-1531.
| Keywords: | ALK5 Inhibitor II, E-616452, SJN 2511 |
| Supplier: | TargetMol |
| Supplier-Nr: | T6337 |
Properties
| Application: | ALK5 inhibitor |
| MW: | 287.32 D |
| Formula: | C17H13N5 |
Database Information
| CAS : | 446859-33-2| Matching products |
| KEGG ID : | K04674 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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