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Description: PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor. Target: Apoptosis, 5-HT Receptor. Smiles: C(Sc1ncnc2nc[nH]c12)c1cccc2ccccc12. References: Trattnig S M , Harpsoe K , Thygesen S B , et al. Discovery of a Novel Allosteric Modulator of 5-HT3 Receptors: INHIBITION ANDPOTENTI ATIONOFCYS-LOOP RECEPTOR SIGNALING THROUGH A CONSERVED TRANSMEMBRANE INTERSUBUNIT SITE[J]. Journal of Biological Chemistry, 2012, 287(30):25241-25254.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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