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Item number: Cay14312-10

PU 02 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 with IC50 values ranging from 0.36 to 1.3 µM for human 5-HT3A, 5-HT3AB, 5-HT3AC, and 5-HT3AE in a FLIPR membrane potential assay using HEK293 cells expressing human recombinant receptors. It is selective for 5-HT3 over other Cys-loop containing...

Keywords:	6-[(1-naphthalenylmethyl)thio]-9H-purine
Application:	5-hydroxytryptamine receptor 3A (5-HT3-A) antagonist
CAS	313984-77-9
MW:	292.4 D

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PU02

Item number: TGM-T8445-100mg

Description: PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor. Target: Apoptosis, 5-HT Receptor. Smiles: C(Sc1ncnc2nc[nH]c12)c1cccc2ccccc12. References: Trattnig S M , Harpsoe K , Thygesen S B , et al. Discovery of a Novel Allosteric Modulator of 5-HT3...

Keywords:	PU-02 , 6-[(1-Naphthalenylmethyl)thio]-9H-purine
Application:	5-hydroxytryptamine receptor 3A (5-HT3-A) antagonist
CAS	313984-77-9
MW:	292.36 D

From 32.00€ *

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