79 products were found matching "K04819"!

Ondansetron (hydrochloride hydrate) (Cay-14999) is an analytical reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal...

Granisetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 3.9 nM) with antiemetic activity. It is selective for 5-HT3 over 5-HT4 receptors (Ki = >1,000 nM). Granisetron (0.3, 1, and 3 mg/kg, p.o.) increases the latency to first vomiting episode and reduces the number of vomiting episodes in a...

Ondansetron (hydrochloride) (CRM) (Cay-21710) is a certified reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal Name:...

Vortioxetine is a multimodal serotonergic agent that acts as a serotonin (5-HT, Cay-14332) reuptake inhibitor (Ki = 1.6 nM) and binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively). It also binds to the beta1-adrenergic receptor (Ki = 46 nM). It acts as an antagonist...

Alosetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Kis = 0.3 and 0.4 nM for the rat cortical and human recombinant receptors, respectively). It is selective for 5-HT3 over 5-HT2 and 5-HT1A receptors (Kis = 6.3 and >100 µM, respectively), as well as alpha1-, beta1-, and beta2- adrenergic, M1,...

Ramosetron is a potent and selective antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.06 nM). It has little or no effect at other 5-HT receptor subtypes or at adrenergic or histamine receptors. Ramosetron competitively blocks serotonin-mediated contraction of the colon. It has applications in...

Tropisetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.8 nM for the mouse receptor). It is selective for 5-HT3 over the 5-HT4 receptor subtype (Ki = 156 nM for the porcine receptor). Tropisetron is also an antagonist of the alpha9 nicotinic acetylcholine receptor (nAChR, IC50 = 166 nM...

Vortioxetine is a multimodal serotonergic agent that acts as a serotonin (5-HT, Cay-14332) reuptake inhibitor (Ki = 1.6 nM) and binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively). It also binds to the beta1-adrenergic receptor (Ki = 46 nM). It acts as an antagonist...

Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a...

Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but...

Anti-Serotonin Receptor 3A Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 3A from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Serotonin Receptor 3A from other sources has...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: 5-HT3A, 5-HT3R, HTR3A Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone,...