PRN1371

Item number	Size	Delivery time	Price
TGM-TQ0015-1mg	1 mg	7 - 10 business days*	74.00€
TGM-TQ0015-2mg	2 mg	7 - 10 business days*	106.00€
TGM-TQ0015-5mg	5 mg	7 - 10 business days*	176.00€
TGM-TQ0015-1mL	1 ml	7 - 10 business days*	222.00€
TGM-TQ0015-10mg	10 mg	7 - 10 business days*	320.00€
TGM-TQ0015-25mg	25 mg	7 - 10 business days*	544.00€
TGM-TQ0015-50mg	50 mg	7 - 10 business days*	787.00€
TGM-TQ0015-100mg	100 mg	7 - 10 business days*	1,080.00€

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Description: PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s:... more

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Product information "PRN1371"

Description: PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R). Target: c-Fms, CSF-1R, FGFR. Smiles: CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCCN3CCN(CC3)C(=O)C=C)c2n1. References: Brameld KA, et al. Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (PRN1371) for the Treatment of Solid Tumors. J Med Chem. 2017 Aug 10,60(15):6516-6527.

Supplier:	TargetMol
Supplier-Nr:	TQ0015

Properties

Application:	Irreversible pan-FGFR inhibitor
MW:	561.46 D
Formula:	C26H30Cl2N6O4

Database Information

CAS :	1802929-43-6\| Matching products
KEGG ID :	K05093 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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