Prexasertib

Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-T4310-1mg	1 mg				7 - 10 business days*	44.00€
TGM-T4310-2mg	2 mg				7 - 10 business days*	67.00€
TGM-T4310-5mg	5 mg				7 - 10 business days*	110.00€
TGM-T4310-10mg	10 mg				7 - 10 business days*	171.00€
TGM-T4310-25mg	25 mg				7 - 10 business days*	338.00€
TGM-T4310-50mg	50 mg				7 - 10 business days*	494.00€
TGM-T4310-100mg	100 mg				7 - 10 business days*	708.00€
TGM-T4310-200mg	200 mg	-	-	-	7 - 10 business days*	934.00€

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Description: Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9... more

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Product information "Prexasertib"

Description: Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). Prexasertib causes double-stranded DNA breaks and replication mutations, leading to apoptosis. Prexasertib has antitumor activity. Target: Apoptosis, Chk. Smiles: COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1. References: King C, et al. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Mol Cancer Ther. 2015 Sep,14(9):2004-13.

Keywords:	LY2606368
Supplier:	TargetMol
Supplier-Nr:	T4310

Properties

Application:	Targets serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] (CHEK1)
MW:	365.39 D
Formula:	C18H19N7O2

Database Information

CAS :	1234015-52-1\| Matching products
KEGG ID :	K02216 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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