3 products were found matching "1234015-52-1"!
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LY2606368
Item number: Cay21490-1
LY2606368 is a checkpoint kinase 1 (Chk1) inhibitor with a Ki value of 0.9 nM against the purified target and IC50 values of In vitro, LY2606368 inhibits the doxorubicin-activated G2/M checkpoint in p53-deficient HeLa cells with an EC50 value of 9 nM. LY2606368, at 25 nM, also significantly induces apoptosis and...
| Keywords: | Prexasertib, 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]-2-pyrazinecarbonitrile |
| Application: | CHK1 inhibitor |
| CAS | 1234015-52-1 |
| MW: | 365.4 D |
From 35.00€
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Prexasertib
Item number: TGM-T4310-100mg
Description: Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. Target: Chk, Apoptosis. Smiles: COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1. References: King C, et al. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent...
| Keywords: | LY2606368 |
| Application: | Targets serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] (CHEK1) |
| CAS | 1234015-52-1 |
| MW: | 365.39 D |
From 48.00€
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LY-2606368
Item number: LKT-L960006.100
CHK1 inhibitor.
| Keywords: | LY 2606368, LY2606368, Prexasertib |
| Application: | CHK1 inhibitor |
| CAS | 1234015-52-1 |
| MW: | 365.4 D |
From 189.00€
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