Pitavastatin calcium
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7... more
Product information "Pitavastatin calcium"
Description: Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions. Target: Apoptosis, Autophagy, Mitophagy, Endogenous Metabolite, HMG-CoA Reductase. Smiles: [Ca++].O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O.O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O. References: Ahmad H, et al. Cardiol Rev, 2010, 18(5):264-267.
| Keywords: | NK-104, itavastatin, Pitavastatin hemicalcium, nisvastatin, P-872441 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2534 |
Properties
| Application: | Targets hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] (HMGCR) |
| MW: | 880.98 D |
| Formula: | C50H46CaF2N2O8 |
Database Information
| CAS : | 147526-32-7| Matching products |
| KEGG ID : | K00021 | Matching products |
| Protein Atlas Nr. : | Metabolism |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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