3 products were found matching "147526-32-7"!
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Pitavastatin (calcium salt)
Item number: Cay15414-10
Pitavastatin is an HMG-CoA reductase inhibitor (Ki = 1.7 nM for the rat liver microsomal enzyme). It inhibits sterol biosynthesis in rat liver and ileum (ED50s = 0.13 and 0.2 mg/kg, respectively) and reduces plasma levels of triglycerides and total cholesterol in dogs. Pitavastatin (0.3 mg/kg) increases survival in...
| Keywords: | Itabastatin, Itavastatin, NK 104, (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic... |
| Application: | HMG-CoA reductase inhibitor |
| CAS | 147526-32-7 |
| MW: | 440.5 D |
From 85.00€
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Pitavastatin calcium
Item number: TGM-T2534-100mg
Description: Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions. Target:...
| Keywords: | NK-104, itavastatin, Pitavastatin hemicalcium, nisvastatin, P-872441 |
| Application: | Targets hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] (HMGCR) |
| CAS | 147526-32-7 |
| MW: | 880.98 D |
From 34.00€
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