O-Desmethyl gefitinib

Item number	Size	Delivery time	Price
TGM-T16369-1mg	1 mg	7 - 10 business days*	48.00€
TGM-T16369-5mg	5 mg	7 - 10 business days*	106.00€
TGM-T16369-1mL	1 ml	7 - 10 business days*	115.00€
TGM-T16369-10mg	10 mg	7 - 10 business days*	169.00€
TGM-T16369-25mg	25 mg	7 - 10 business days*	340.00€
TGM-T16369-50mg	50 mg	7 - 10 business days*	544.00€
TGM-T16369-100mg	100 mg	7 - 10 business days*	780.00€

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Description: O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human... more

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Product information "O-Desmethyl gefitinib"

Description: O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 activity. Target: EGFR. Smiles: Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1. References: Kobayashi H, et al. Effects of polymorphisms in CYP2D6 and ABC transporters and side effects induced by gefitinib on the pharmacokinetics of the gefitinib metabolite, O-desmethyl gefitinib. Med Oncol. 2016 Jun,33(6):57.

Supplier:	TargetMol
Supplier-Nr:	T16369

Properties

Application:	Metabolite, EGFR inhibitor
MW:	432.88 D
Formula:	C21H22ClFN4O3

Database Information

CAS :	847949-49-9\| Matching products
KEGG ID :	K04361 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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