MR837
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MR837 is an inhibitor of the histone-lysine N-methyltransferase NSD2 (IC50 = 24. µM). It binds to... more
Product information "MR837"
MR837 is an inhibitor of the histone-lysine N-methyltransferase NSD2 (IC50 = 24. µM). It binds to the NSD2 PWWP1 domain (Kd = 7 µM), which binds methylated histones, and inhibits the protein-protein interaction between NSD2 and histone H3. in U2OS cells (IC50 = 17. µM). InChI: InChI=1S/C16H14N2OS/c17-10-12-3-5-13(6-4-12)16(19)18(14-7-8-14)11-15-2-1-9-20-15/h1-6,9,14H,7-8,11H2 InChIKey: WYAGGMZTARRIDX-UHFFFAOYSA-N SMILES: N#CC1=CC=C(C(N(CC2=CC=CS2)C3CC3)=O)C=C1
| Keywords: | 4-cyano-N-cyclopropyl-N-(2-thienylmethyl)-benzamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43711 |
Properties
| Application: | NSD2 ([histone H3]-lysine36 N-dimethyltransferase) inhibitor |
| MW: | 282.36 D |
| Formula: | C16H14N2OS |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1210906-48-1| Matching products |
| KEGG ID : | K11424 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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