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Item number: Cay43711-10

MR837 is an inhibitor of the histone-lysine N-methyltransferase NSD2 (IC50 = 24. µM). It binds to the NSD2 PWWP1 domain (Kd = 7 µM), which binds methylated histones, and inhibits the protein-protein interaction between NSD2 and histone H3. in U2OS cells (IC50 = 17. µM). InChI:...

Keywords:	4-cyano-N-cyclopropyl-N-(2-thienylmethyl)-benzamide
Application:	NSD2 ([histone H3]-lysine36 N-dimethyltransferase) inhibitor
CAS	1210906-48-1
MW:	282.36 D

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MR837

Item number: TGM-T8879-100mg

Description: MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist. Target: Histone Methyltransferase. Smiles: O=C(N(Cc1cccs1)C1CC1)c1ccc(cc1)C#N

Keywords:	ZINC30303842 , NSD2-PWWP1 antagonist 3f
CAS	1210906-48-1
MW:	282.36 D

From 33.00€ *

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