Macitentan-d4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T11934-1mg	1 mg				5 - 10 business days*		248.00€
TGM-T11934-5mg	5 mg				5 - 10 business days*		625.00€

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Description: Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be... more

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Product information "Macitentan-d4"

Description: Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases. Smiles: N(S(NCCC)(=O)=O)C=1C(=C(OC(C(OC=2N=CC(Br)=CN2)([2H])[2H])([2H])[2H])N=CN1)C3=CC=C(Br)C=C3. References: Corallo C, et al. Bosentan and macitentan prevent the endothelial-to-mesenchymal transition (EndoMT) in systemic sclerosis: in vitro study. Arthritis Res Ther. 2016 Oct 6,18(1):228.

Keywords:	Macitentan D4, ACT-064992 D4
Supplier:	TargetMol
Supplier-Nr:	T11934

Properties

Application:	GC-MS, LC-MS, internal standard, quantification, dual EDNRA / EDNRB antagonist
MW:	592.3 D
Formula:	C19H20Br2N6O4S

Database Information

CAS :	1258428-05-5\| Matching products
KEGG ID :	K04197 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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