- Search results for 1258428-05-5
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2 products were found matching "1258428-05-5"!
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Item number: Cay28522-1
Macitentan-d4 is intended for use as an internal standard for the quantification of macitentan (Cay-23304) by GC- or LC-MS. Macitentan is a dual antagonist of the endothelin (ET) receptors type A and B (IC50s = 0.5 and 391 nM in a radioligand binding assay using recombinant ETA and ETB, respectively). Macitentan...
| Keywords: | ACT-064992-d4, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy-1,1,2,2-d4]-4-pyrimidinyl]-N'-propyl-sulfamide |
| Application: | GC-MS, LC-MS, internal standard, quantification, dual EDNRA / EDNRB antagonist |
| CAS | 1258428-05-5 |
| MW: | 592.3 D |
697.00€
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Item number: TGM-T11934-1mg
Description: Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases. Smiles:...
| Keywords: | Macitentan D4, ACT-064992 D4 |
| Application: | GC-MS, LC-MS, internal standard, quantification, dual EDNRA / EDNRB antagonist |
| CAS | 1258428-05-5 |
| MW: | 592.3 D |
From 248.00€
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