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Macitentan-d4
Macitentan-d4

Item number: Cay28522-1

Macitentan-d4 is intended for use as an internal standard for the quantification of macitentan (Cay-23304) by GC- or LC-MS. Macitentan is a dual antagonist of the endothelin (ET) receptors type A and B (IC50s = 0.5 and 391 nM in a radioligand binding assay using recombinant ETA and ETB, respectively). Macitentan...
Keywords: ACT-064992-d4, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy-1,1,2,2-d4]-4-pyrimidinyl]-N'-propyl-sulfamide
Application: GC-MS, LC-MS, internal standard, quantification, dual EDNRA / EDNRB antagonist
CAS 1258428-05-5
MW: 592.3 D
697.00€ *
Review
Macitentan-d4
Macitentan-d4

Item number: TGM-T11934-1mg

Description: Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases. Smiles:...
Keywords: Macitentan D4, ACT-064992 D4
Application: GC-MS, LC-MS, internal standard, quantification, dual EDNRA / EDNRB antagonist
CAS 1258428-05-5
MW: 592.3 D
From 248.00€ *
Review