Luzindole
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Larger quantity required? Request bulk
Description: Luzindole (N-0774) is a selective melatonin receptor antagonist that inhibits... more
Product information "Luzindole"
Description: Luzindole (N-0774) is a selective melatonin receptor antagonist that inhibits experimental autoimmune encephalomyelitis and exhibits antidepressant-like activity. It preferentially targets MT2 (Mel1b) over MT1 (Mel1a), with Ki values of 10.2 nM for human MT2 and 158 nM for MT1. Target: Melatonin Receptor, MT Receptor. Smiles: CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12. References: Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar,355(3):365-75.
| Keywords: | N-0774 |
| Supplier: | TargetMol |
| Supplier-Nr: | T15795 |
Properties
| Application: | Melatonin receptor MTNR1B antagonist |
| MW: | 292.37 D |
| Formula: | C19H20N2O |
Database Information
| CAS : | 117946-91-5| Matching products |
| KEGG ID : | K04286 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319 |
| P Phrases: | P264, P270, P280, P301+310, P302+352, P305+351+338, P321, P330, P332+313, P337+313, P362+364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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