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Item number: TGM-T15795-100mg

Description: Luzindole (N-0774) is a selective melatonin receptor antagonist that inhibits experimental autoimmune encephalomyelitis and exhibits antidepressant-like activity. It preferentially targets MT2 (Mel1b) over MT1 (Mel1a), with Ki values of 10.2 nM for human MT2 and 158 nM for MT1. Target: Melatonin...

Keywords:	N-0774
Application:	Melatonin receptor MTNR1B antagonist
CAS	117946-91-5
MW:	292.37 D

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Luzindole

Item number: Cay15998-10

In addition to intrinsic antioxidant activities, melatonin (Cay-14427) evokes its effects through the G protein-coupled receptors MT1A (MT1) and MT1B (MT2). Luzindole is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively). Luzindole is used...

Keywords:	N-0774, N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]-acetamide
Application:	Melatonin receptor MTNR1B antagonist
CAS	117946-91-5
MW:	292.3 D

From 85.00€ *

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