JNJ-42847922
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An orexin receptor 2 antagonist (Ki = 10 nM), selective for OX2R over OX1R (Ki = 794 nM) and a... more
Product information "JNJ-42847922"
An orexin receptor 2 antagonist (Ki = 10 nM), selective for OX2R over OX1R (Ki = 794 nM) and a panel of 50 receptors, ion channels, and transporters at 1 µM, reduces the latency to NREM sleep onset and increases the duration of NREM sleep in rats at 3, 10, and 30 mg/kg. Formulation: A solid. InChI: InChI=1S/C21H22FN7O/c1-13-8-14(2)26-21(25-13)28-11-15-9-27(10-16(15)12-28)20(30)19-17(22)4-3-5-18(19)29-23-6-7-24-29/h3-8,15-16H,9-12H2,1-2H3. InChIKey: SQOCEMCKYDVLMM-UHFFFAOYSA-N. SMILES: O=C(N1CC(CN(C2=NC(C)=CC(C)=N2)C3)C3C1)C4=C(F)C=CC=C4N5N=CC=N5
| Keywords: | MIN-202, [5-(4,6-dimethyl-2-pyrimidinyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl][2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl]-methanone |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 41854 |
Properties
| Application: | Orexin receptor 2 antagonist |
| Immunogen: | 407.5 |
| MW: | 407.5 D |
| Formula: | C21H22FN7O |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1293281-49-8| Matching products |
| KEGG ID : | K04239 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H312, H315, H319, H332, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P361+364, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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