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Item number: TGM-T12877L-100mg

Description: Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R). Target: OX Receptor. Smiles:...

Keywords:	JNJ-42847922
Application:	Targets hypocretin (orexin) receptor 2 (HCRTR2)
CAS	1293281-49-8
MW:	407.44 D

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JNJ-42847922

Item number: Cay41854-10

An orexin receptor 2 antagonist (Ki = 10 nM), selective for OX2R over OX1R (Ki = 794 nM) and a panel of 50 receptors, ion channels, and transporters at 1 µM, reduces the latency to NREM sleep onset and increases the duration of NREM sleep in rats at 3, 10, and 30 mg/kg. Formulation: A solid. InChI:...

Keywords:	MIN-202,...
Application:	Orexin receptor 2 antagonist
CAS	1293281-49-8
MW:	407.5 D

From 116.00€ *

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