Indole-3-carbinol

Indole-3-carbinol (I3C) is a natural phytochemical produced in crucifers by the action of myrosinase on glucobrassinin. It has been shown to have anti-cancer effects, at least in part through inhibition of NF-kappaB and Akt signaling pathways. I3C may undergo a condensation reaction in vivo, leading to the production of 3,3'-diindolylmethane (Cay-15927), which alters the expression of oncogenes and tumor suppressor genes.Formal Name: 1H-indole-3-methanol. CAS Number: 700-06-1. Synonyms: 3-hydroxymethyl Indole, I3C, Indinol, 1H-Indole-3-methanol, 3-Indolylmethanol, NSC 525801. Molecular Formula: C9H9NO. Formula Weight: 147.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 3 mg/ml, Ethanol: 10 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 220, 279 nm. SMILES: OCC1=CNC2=C1C=CC=C2. InChi Code: InChI=1S/C9H9NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-5,10-11H,6H2. InChi Key: IVYPNXXAYMYVSP-UHFFFAOYSA-N.