GW843682X
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3... more
Product information "GW843682X"
Description: GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM). Target: VEGFR, PLK, Aurora Kinase, PDGFR, CDK. Smiles: COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(N)=O)c2cc1OC. References: Didier C, et al. Evaluation of Polo-like Kinase 1 inhibition on the G2/M checkpoint in Acute Myelocytic Leukaemia. Eur J Pharmacol. 2008 Sep 4,591(1-3):102-5.
| Keywords: | GW843682 |
| Supplier: | TargetMol |
| Supplier-Nr: | T15454 |
Properties
| Application: | Cell-permeable PLK inhibitor |
| MW: | 477.46 D |
| Formula: | C22H18F3N3O4S |
Database Information
| CAS : | 660868-91-7| Matching products |
| KEGG ID : | K08862 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335, H413 |
| P Phrases: | P261, P264, P271, P273, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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