14 products were found matching "K08862"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PLK3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PLK3. Next,...

Active human Plk3 (GenBank Accession No. NM_004073), (a.a. 58-339) with N-terminal HIS6 tag, MW=36.7 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

GW843682X is a reversible, cell-permeable polo-like kinase (PLK) inhibitor. It selectively inhibits Plk1 and Plk3 (IC50s = 2.2 and 9.1 nM, respectively) over PDGFR1beta, VEGFR2, Aurora A, and Cdk2/cyclin A (IC50s = 160, 360, 4,800, and 7,600 nM, respectively), as well as over 30 other kinases, in a cell-free assay....

Human N-terminal MBP tagged Plk3 polo box domain (GenBank Accession No.NM_004073/NP_004064), (amino acids 335-646) with C-terminal His tag, MW=80.5 kDa, expressed in an E.coli expression system.

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Polo-like kinase 3 Protein function: Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and...

Polo-like kinases (Plks) are serine/threonine kinases with key roles in cell cycling. BI-6727 is a dihydropteridinone that inhibits Plk1, Plk2, and Plk3 (IC50s = 0.87, 5, and 56 nM, respectively), inducing mitotic arrest and apoptosis. It inhibits proliferation of multiple cancer cell lines with EC50 values ranging...

Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi...

Protein function: Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates ATF2, BCL2L1, CDC25A,...

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular...

CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the...

Human Plk3 (GenBank Accession No. NM_004073), (a.a. 58-339) with N-terminal HIS6 tag, , MW 36.7kD, expressed in an Baculovirus infected Sf9 cell expression system. Purity: >80% by SDS-PAGE. Specific Activity: 500 U/mg. One unit is defined as the amount of enzyme that will phosphorylate 1nmol of casein substrate...