GSK2881078

GSK2881078 is a selective androgen receptor modulator (SARM). It induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM), an effect that can be inhibited by the non-steroidal AR antagonist bicalutamide (Cay-14250).Formal Name: 1-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile. CAS Number: 1539314-06-1. Molecular Formula: C14H13F3N2O2S. Formula Weight: 330.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml, Ethanol: 20 mg/ml. lambdamax: 243, 303 nm. SMILES: CS(C[C@@H](C)N1C2=CC=C(C#N)C(C(F)(F)F)=C2C=C1)(=O)=O. InChi Code: InChI=1S/C14H13F3N2O2S/c1-9(8-22(2,20)21)19-6-5-11-12(19)4-3-10(7-18)13(11)14(15,16)17/h3-6,9H,8H2,1-2H3/t9-/m1/s1. InChi Key: SKDVMPZQJMZEAC-SECBINFHSA-N.