GNE-131

NEW

Item number	Size	Manual	Delivery time	Price
Cay45386-1	1 mg	-	6 - 10 business days*	91.00€
Cay45386-5	5 mg	-	6 - 10 business days*	408.00€
Cay45386-10	10 mg	-	6 - 10 business days*	679.00€
Cay45386-25	25 mg	-	6 - 10 business days*	1,354.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

An inhibitor of Nav1.7 (IC50 = 0.003 µM), selective for Nav1.7 over Nav1.1, Nav1.2, Nav1.5, and... more

Close menu

Product information "GNE-131"

An inhibitor of Nav1.7 (IC50 = 0.003 µM), selective for Nav1.7 over Nav1.1, Nav1.2, Nav1.5, and Nav1.6 (IC50s = 0.045, 0.007, 0.110, and 0.092 µM, respectively), reduces aconitine-induced nocifensive behavior in a transgenic mouse model of IEM at 30 mg/kg. SMILES: O=[S](NC1=NN=C2C=C(C(C3CC3)=CN21)OCC4(C[C@@H](C5)C6)C[C@@H]6C[C@@H]5C4)(C7CC7)=O. InChi Code: InChI=1S/C23H30N4O3S/c28-31(29,18-3-4-18)26-22-25-24-21-8-20(19(12-27(21)22)17-1-2-17)30-13-23-9-14-5-15(10-23)7-16(6-14)11-23/h8,12,14-18H,1-7,9-11,13H2,(H,25,26)/t14-,15+,16-,23?. InChi Key: FPERPEQIXLOVIK-QUXYOMGYSA-N

Keywords:	N-[6-cyclopropyl-7-(tricyclo[3.3.1.13,7]dec-1-ylmethoxy)-1,2,4-triazolo[4,3-a]pyridin-3-yl]-cyclopropanesulfonamide
Supplier:	Cayman Chemical
Supplier-Nr:	45386

Properties

Application:	Nav1.7 (SCN9A) inhibitor
MW:	442.58 D
Formula:	C23H30N4O3S
Purity:	>95%
Format:	Solid

Database Information

CAS :	1629063-81-5\| Matching products
KEGG ID :	K04841 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

View product citations for antibody 45386 on CiteAb

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "GNE-131"

Write a review