The following products have been found matching your search "K04841": 15

1 from 2 pages
No results were found for the filter!
Bupivacaine
Bupivacaine

Item number: Cay16618-500

Bupivacaine is a sodium channel blocker and local anesthetic. It inhibits sodium currents in rat dorsal horn neurons in a concentration-dependent manner and inhibits synaptic transmission in rat sympathetic ganglia, increasing the firing threshold when used at a concentration of 200 nM. Bupivacaine (10 µM) blocks...
Keywords: 1-butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
Application: Sodium influx blocker
CAS 38396-39-3
MW: 288.4 D
From 32.00€ *
Review
Anti-NAV1.7, clone S68-6
Anti-NAV1.7, clone S68-6

Item number: 200-301-G21

Anti-NAV1.7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with NAV1.7 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against other Nav channels. Cross-reactivity with NAV1.7 from other sources has not been...
Keywords: Anti-PN1, Anti-NENA, Anti-SCN9A, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel,...
Application: IHC, IFM, IP, WB
Reactivity: Human, Mouse, Rat
506.00€ *
Review
Anti-Nav1.7 Na+ Channel, clone S68-6
Anti-Nav1.7 Na+ Channel, clone S68-6

Item number: ARG56140.50

Protein function: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical...
Keywords: Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium...
Application: IHC (paraffin), WB
Reactivity: Hamster, Human, Mouse, Rat
467.00€ *
Review
Buy One Get One 50% Off
Anti-SCN9A
Anti-SCN9A

Item number: E-AB-16052.120

This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. Protein function: Mediates the voltage-dependent...
Keywords: Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium...
Application: IHC, ELISA
Reactivity: Human
From 63.00€ *
Review
Benzonatate
Benzonatate

Item number: Cay23936-1

Benzonatate is a reversible voltage-gated sodium channel blocker. It blocks Nav1.7 currents in a concentration- and voltage-dependent manner (IC50s = 5.9 and 1.4 µM at holding potentials of -100 and -70 mV, respectively) and inhibits action potential firing in catecholamine A differentiated (CAD) cells. Benzonatate...
Keywords: 4-(butylamino)-benzoic acid, 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester
Application: Reversible voltage-gated sodium channel blocker
CAS 104-31-4
MW: 603.8 D
From 44.00€ *
Review
Buy One Get One 50% Off
Anti-SCN9A
Anti-SCN9A

Item number: E-AB-12861.120

This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. Protein function: Mediates the voltage-dependent...
Keywords: Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium...
Application: IHC, ELISA
Reactivity: Human
From 63.00€ *
Review
PF-05089771 (tosylate)
PF-05089771 (tosylate)

Item number: Cay24449-10

PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50s = 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50s = 0.11-25 µM), L-type calcium, and KvLQT and hERG potassium channels (IC50s =...
Keywords: 4-[2-(3-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-4-benzenesulfonamide,...
Application: Nav1.7 blocker
CAS 1430806-04-4
MW: 672.6 D
From 100.00€ *
Review
NaV1.7 - HEK293 recombinant human stable cell line (2x10(6) cells)
NaV1.7 - HEK293 recombinant human stable cell line...

Item number: BPS-60507

Nav1.7 (Genbank # Q15858) is present at the endings of pain-sensing nerves, the nociceptors, close to region where the impulse is initiated. The Nav1.7 channel produces a rapidly activating and inactivating current which is sensitive to level of tetrodotoxin. Knockout mice that lack Nav1.7 in nociceptors showed...
Keywords: PN1, NENA, SCN9A, hNE-Na, Peripheral sodium channel 1, Neuroendocrine sodium channel, Sodium channel protein type 9...
Application: Drug screening, Functional assays
10,274.00€ *
Review
Tolperisone (hydrochloride)
Tolperisone (hydrochloride)

Item number: Cay26078-5

Tolperisone is a piperidine that acts as an inhibitor of voltage-gated sodium channels with an IC50 value of 198 µM, for inhibition of peak sodium currents evoked by step depolarizations in dorsal root ganglion (DRG) neurons, in vitro. Tolperisone acts as an antispastic agent that attenuates monosynaptic,...
Keywords: N-553, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone, monohydrochloride
Application: Voltage-gated sodium channel inhibitor, Muscle relaxant
CAS 3644-61-9
MW: 281.8 D
From 187.00€ *
Review
Anti-SCN9A
Anti-SCN9A

Item number: ABD-8C18819

Custom conjugation services for this antibody as available (eg. labeling of Anti-SCN9A with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5,...
Keywords: Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium...
Application: IHC, ELISA
Reactivity: Human, Mouse
230.00€ *
Review
Ambroxol Hydrochloride
Ambroxol Hydrochloride

Item number: LKT-A4806.1

Expectorant.
Keywords: Abramen, Ambril, Duramucal, Fluibron, Fluixol, Mucolear, Mucosolvan, 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]-...
Application: Voltage-gated sodium channel (SCN1A, SCN2A, SCN3A, SCN4A, SCN5A, SCN8A, SCN9A) blocker
CAS 23828-92-4
MW: 414.57 D
From 66.00€ *
Review
Anti-Nav1.7 (PN1, Type IX Voltage-gated Sodium Channel, NENA, NE, Scn9a)
Anti-Nav1.7 (PN1, Type IX Voltage-gated Sodium Channel,...

Item number: N0530-25.50

Applications:, Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot (ECL): 1:200. Rat brain membranes, Immunohistochemistry: Frozen rat dorsal root ganglion., Dilutions should be made using a carrier protein such as BSA (1-3%), Optimal...
Keywords: Anti-Peripheral sodium channel 1, Anti-Sodium channel protein type 9 subunit alpha, Anti-Sodium channel protein type IX...
Application: IHC, WB
Reactivity: Rat
638.00€ *
Review
1 from 2 pages