Foretinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of... more
Product information "Foretinib"
Description: Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR. Target: Tie-2, c-Met/HGFR, VEGFR. Smiles: COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1. References: Qian F, et al. Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases. Cancer Res, 2009, 69(20), 8009-8016.
| Keywords: | EXEL-2880, GSK1363089, XL880, GSK089 |
| Supplier: | TargetMol |
| Supplier-Nr: | T3113 |
Properties
| Application: | Targets kinase insert domain protein receptor [EC:2.7.10.1] (KDR, VEGFR2, CD309) |
| MW: | 632.65 D |
| Formula: | C34H34F2N4O6 |
Database Information
| CAS : | 849217-64-7| Matching products |
| KEGG ID : | K05098 | Matching products |
| Protein Atlas Nr. : | Tyrosine Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H373 |
| P Phrases: | P260, P264, P270, P314, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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