3 products were found matching "849217-64-7"!
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Foretinib
Item number: Cay16249-1
Foretinib is a broad-spectrum tyrosine kinase (TK) inhibitor that targets members of the HGF and VEGF receptor TK families, as well as KIT, Flt-3, PDGFRbeta, and Tie-2, at nanomolar concentrations. It blocks HGF-induced Met phosphorylation and VEGF-induced ERK phosphorylation, preventing HGF-induced responses in...
| Keywords: | GSK1363089, XL880,... |
| Application: | VEGFR2 / MET inhibitor |
| CAS | 849217-64-7 |
| MW: | 632.7 D |
From 43.00€
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Foretinib
Item number: LKT-F5968.5
Foretinib is an inhibitor of ROS1, MET, Ron, Axl, Tie-2, and VEGFR2 that exhibits anticancer chemotherapeutic and anti-angiogenic activities. In subjects with squamous cell carcinoma, foretinib decreases tumor size. In hepatocellular carcinoma cells, foretinib increases expression of p27 and Bim, decreases...
| Keywords: | GSK-1363089, GSK1363089 |
| Application: | VEGFR2 tyrosine kinase inhibitor, Met proto-oncogene (c-Met) inhibitor |
| CAS | 849217-64-7 |
| MW: | 632.65 D |
From 144.00€
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Foretinib
Item number: SYN-1129-M001
Soluble in DMSO. Foretinib is a novel MET and VEGFR2 kinase inhibitor with IC(50) values of 0.4 and 0.8nM for MET and VEGFR2 respectively. Target: VEGFR2 - MET , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | GSK-1363089, EXEL-2880 |
| Application: | VEGFR2 / MET inhibitor |
| CAS | 849217-64-7 |
| MW: | 632,7 D |
From 139.00€
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