Folinic Acid, Calcium Salt (N5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid, Leucovorin, calcium

Folinic Acid is an intermediate product of the metabolism of folic acid and is used as a tissue culture additive. Folinic acid is an antidote to folic acid antagonists such as methotrexate which block the conversion of folic acid into folinic acid. Synonyms: L-N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]glutamic Acid Calcium Salt, Calcium 5-formyltetrahydrofolate, Calcium L-Folinate, Calcium Folinate, Calcium Leucovorin, Folidan, Folinic Acid Calcium Salt, Lederfoline, Leucovorin Calcium, Leucovorin Calcium Salt, NSC 3590, Rescuvolin, Wellcovorin, USP Folic Acid Related Compound A, CAS No: 1492-18-8, Molecular Formula: C??H??CaN?O?, Molecular Weight: 511.51, Appearance: White or light yellow powder, micro-yellow crystalline or amorphous powder, no visible evidence of contamination by foreign matter. Purity: 95.0-105.0%, Water: <17%, Heavy Metals: <0.005%, pH: 6.8-8.0, Ethyl Ether: <1%, Ethanol: <5%, Solubility: Sparingly soluble in water, Endotoxin: < 0.5EU/mg, Total Aerobic Microbial Count: <1000CFU/g, Molds and Yeasts Total Count: <100CFU/g, Escherichia coli: Absent, Identification (IR): Conforms