Fluvastatin (sodium salt)

Fluvastatin (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010337-10 10 mg -

6 - 10 business days*

25.00€
Cay10010337-25 25 mg -

6 - 10 business days*

55.00€
Cay10010337-50 50 mg -

6 - 10 business days*

83.00€
Cay10010337-100 100 mg -

6 - 10 business days*

148.00€
 
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme) that binds to... more
Product information "Fluvastatin (sodium salt)"
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme) that binds to the HMG-CoA binding site. It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin (2 mg/kg per day) inhibits increases in serum cholesterol, triglycerides, phospholipids, and thiobarbituric acid-reactive substances (TBARS) levels, as well as vascular angiotensin converting enzyme (ACE) activity in rabbits fed a high-cholesterol diet. It increases survival in a mouse model of myocardial infarction when administered at a dose of 10 mg/kg per day. Formulations containing fluvastatin have been used in the treatment of hypercholesterolemia and the prevention of cardiovascular disease. Formal Name: 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate. Molecular Formula: C24H25FNO4 . Na [XH2O]. Formula Weight: 410.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 0.5 mg/ml, PBS (pH 7.2): 0.2 mg/ml. lambdamax: 233, 305 nm. SMILES: FC1=CC=C(C=C1)C2=C(/C=C/C(O)CC(O)CC([O-])=O)N(C(C)C)C3=C2C=CC=C3.[Na+].O. InChi Code: InChI=1S/C24H26FNO4.Na.H2O/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30,,/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30),,1H2/q,+1,/p-1/b12-11+,,. InChi Key: KKEMYLLTGGQWCE-YHPRVSEPSA-M.
Keywords: 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate
Supplier: Cayman Chemical
Supplier-Nr: 10010337

Properties

Application: Hydroxymethylglutaryl-coenzyme A reductase inhibitor
MW: 410.5 D
Formula: C24H25FNO4 . Na [XH2O]
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 93957-55-2| Find alternatives
KEGG ID : K01641 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H350
P Phrases: P201, P202, P280, P308+313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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