Fidarestat

Item number	Size	Delivery time	Price
TGM-T15281-1mg	1 mg	7 - 10 business days*	48.00€
TGM-T15281-5mg	5 mg	7 - 10 business days*	235.00€
TGM-T15281-10mg	10 mg	7 - 10 business days*	377.00€

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Description: Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 µM, and 1.8 µM for... more

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Product information "Fidarestat"

Description: Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 µM, and 1.8 µM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potential to treat diabetic disease. Target: Reductase. Smiles: NC(=O)[C@@H]1C[C@]2(NC(=O)NC2=O)c2cc(F)ccc2O1. References: Ruiz FX, et al. X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. Chem Biol Interact. 2013 Feb 25,202(1-3):178-85.

Keywords:	SNK 860
Supplier:	TargetMol
Supplier-Nr:	T15281

Properties

Application:	Targets aldehyde reductase [EC:1.1.1.21] (AKR1B)
MW:	279.22 D
Formula:	C12H10FN3O4
Format:	32160405

Database Information

CAS :	136087-85-9\| Matching products
KEGG ID :	K00011 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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