- Search results for K00011
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89 products were found matching "K00011"!
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Item number: ELK-ELK0749.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse AKR1B1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse AKR1B1....
Keywords: | AR, Akr1b1, Aldose reductase, Aldehyde reductase, Aldo-keto reductase family 1 member B3, Aldo-keto reductase family 1... |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: ELK-ELK0750.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat AKR1B1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat AKR1B1. Next,...
Keywords: | AR, Akr1b4, Akr1b1, Aldose reductase, Aldehyde reductase, Aldo-keto reductase family 1 member B1 |
Application: | ELISA |
Species reactivity: | rat |
From 365.00€
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Item number: Cay19196-10
Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol. It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities. Syringic acid has been shown to inhibit aldose...
Keywords: | 3,5-dimethoxy-4-hydroxy Benzoic Acid, 3,5-dimethyl ether Gallic Acid, NSC 2129, 4-hydroxy-3,5-dimethoxy-benzoic acid |
Application: | Aldose reductase inhibitor |
CAS | 530-57-4 |
MW: | 198.2 D |
From 43.00€
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Item number: Cay10004387-10
Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid |
Application: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
CAS | 49627-27-2 |
MW: | 340.4 D |
From 43.00€
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Item number: Cay19189-5
Statil is an aldose reductase inhibitor that blocks the conversion of glucose to sorbitol. It demonstrates selectivity for aldose reductase 2 over aldose reductase 1 with Ki values of 7.7 nM and 60 µM, respectively. Statil has been shown to prevent diabetes-induced alterations of the cardiovascular system in 14-day...
Keywords: | ICI 128436, MK-538, Ponalrestat, 3-[(4-bromo-2-fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid |
Application: | Aldose reductase inhibitor |
CAS | 72702-95-5 |
MW: | 391.2 D |
From 43.00€
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Item number: Cay15214-5
Epalrestat is an inhibitor of aldose reductase (IC50s = 0.01 and 0.26 µM for rat lens and human placenta aldose reductase, respectively). It inhibits glucose-induced sorbitol accumulation in isolated rat lens, rat sciatic nerve, and human erythrocytes (IC50s = 1.5, 5, and 1.5 µM, respectively). It decreases high...
Keywords: | ONO-2235, 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid |
Application: | Aldose reductase inhibitor |
CAS | 82159-09-9 |
MW: | 319.4 D |
From 98.00€
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Item number: Cay16805-5
Sulindac (Cay-10004386) is a non-steroidal anti-inflammatory drug that has an extensive epidemiology documenting reduced human colorectal cancer. In mouse models, sulindac was found not only to inhibit the enzymatic activity of polyp-associated COX-2, but also to downregulate the expression of colonic COX-2 protein...
Keywords: | Exisulind, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid |
Application: | Aldose reductase inhibitor |
CAS | 59864-04-9 |
MW: | 372.4 D |
From 62.00€
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Item number: ARG54099.100
Protein function: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. [The UniProt Consortium]
Keywords: | Anti-AR, Anti-ALDR1, Anti-AKR1B1, EC=1.1.1.21, Anti-Aldose reductase, Anti-Aldehyde reductase, Anti-Aldo-keto reductase... |
Application: | WB |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
624.00€
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Item number: ARG55439.100
Protein function: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. [The UniProt Consortium]
Keywords: | Anti-AR, Anti-ALDR1, Anti-AKR1B1, EC=1.1.1.21, Anti-Aldose reductase, Anti-Aldehyde reductase, Anti-Aldo-keto reductase... |
Application: | WB, IHC (paraffin), ICC, IF |
Host: | Rabbit |
Species reactivity: | human |
584.00€
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Item number: ARG55470.100
Protein function: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. [The UniProt Consortium]
Keywords: | Anti-AR, Anti-ALDR1, Anti-AKR1B1, EC=1.1.1.21, Anti-Aldose reductase, Anti-Aldehyde reductase, Anti-Aldo-keto reductase... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
624.00€
*
Item number: ARG55510.100
Protein function: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. [The UniProt Consortium]
Keywords: | Anti-ARP, Anti-hARP, Anti-ARL-1, Anti-AKR1B11, Anti-AKR1B10, EC=1.1.1.-, Anti-SI reductase, Anti-Aldose reductase-like,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
624.00€
*
Item number: ARG64466.100
Protein function: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. [The UniProt Consortium]
Keywords: | Anti-ARP, Anti-hARP, Anti-ARL-1, Anti-AKR1B11, Anti-AKR1B10, EC=1.1.1.-, Anti-SI reductase, Anti-Aldose reductase-like,... |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human |
784.00€
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