EOAI3402143
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
EOAI3402143 is an inhibitor of ubiquitin-specific protease 9X (USP9X), USP24, and USP5. It... more
Product information "EOAI3402143"
EOAI3402143 is an inhibitor of ubiquitin-specific protease 9X (USP9X), USP24, and USP5. It inhibits the catalytic domain of USP9X (IC50 = 1. µM). EOAI3402143 (5 µM) inhibits USP9X, USP24, and USP5 in MM.1S multiple myeloma cells. It inhibits the growth of vemurafenib-sensitive and -resistant A375 melanoma cells (IC50s = 1 µM). In vivo, EOAI3402143 (15 mg/kg) reduces tumor volume in MM.1S and A375 mouse xenograft models.. Solulibility: DMSO: Sparingly soluble: 1-10 mg/ml: .
| Keywords: | G9, 2E-cyano-3-(3,6-dichloro-2-pyridinyl)-N-[1-[4-[2-(4-morpholinyl)ethoxy]phenyl]butyl]-2-propenamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43117 |
Properties
| Application: | USP9X/USP24/USP5 inhibitor |
| MW: | 503.42 D |
| Formula: | C25H28Cl2N4O3 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1699750-95-2| Matching products |
| KEGG ID : | K11840 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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