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EOAI3402143
EOAI3402143

Item number: Cay43117-10

EOAI3402143 is an inhibitor of ubiquitin-specific protease 9X (USP9X), USP24, and USP5. It inhibits the catalytic domain of USP9X (IC50 = 1. µM). EOAI3402143 (5 µM) inhibits USP9X, USP24, and USP5 in MM.1S multiple myeloma cells. It inhibits the growth of vemurafenib-sensitive and -resistant A375 melanoma cells...
Keywords: G9, 2E-cyano-3-(3,6-dichloro-2-pyridinyl)-N-[1-[4-[2-(4-morpholinyl)ethoxy]phenyl]butyl]-2-propenamide
Application: USP9X/USP24/USP5 inhibitor
CAS 1699750-95-2
MW: 503.42 D
From 275.00€ *
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EOAI3402143
EOAI3402143

Item number: TGM-T11209-10mg

Description: EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth. Target: DUB. Smiles: CCCC(NC(=O)C(=C\c1nc(Cl)ccc1Cl)\C#N)c1ccc(OCCN2CCOCC2)cc1. References: Potu...
CAS 1699750-95-2
MW: 503.42 D
From 57.00€ *
Review