54 products were found matching "K11840"!

Protein function: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of...

EOAI3402143 is an inhibitor of ubiquitin-specific protease 9X (USP9X), USP24, and USP5. It inhibits the catalytic domain of USP9X (IC50 = 1. µM). EOAI3402143 (5 µM) inhibits USP9X, USP24, and USP5 in MM.1S multiple myeloma cells. It inhibits the growth of vemurafenib-sensitive and -resistant A375 melanoma cells...

Protein function: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Deubiquitinates DDB2, preventing its proteasomal degradation. [The UniProt Consortium]

Protein function: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of...

This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding...

Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into two subgroups: ubiquitin-specific proteases (USPs) and ubiquitin-specific COOH-terminal hydrolases...

Human USP9X also known as Ubiquitin Specific Peptidase 9 X-Linked, FAM, DFFRX, Ubiquitin Thioesterase FAF-X, MRXS99 and Deubiquitinating Enzyme FAF-X, GenBank Accession No. NM_001039591, a.a. 1559-1995 with N-terminal His-tag and C-terminal FLAG-tag, expressed HEK293 expression system. MW = 53 kDa.

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed...

Protein function: Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. [The UniProt...

Protein function: Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. [The UniProt...

Protein function: Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. [The UniProt...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Probable ubiquitin carboxyl-terminal hydrolase FAF-X is an enzyme that in humans is encoded by the USP9X gene. This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on...