Defactinib hydrochloride

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T15092-2mg	2 mg				7 - 10 business days*		43.00€
TGM-T15092-5mg	5 mg				7 - 10 business days*		67.00€

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Description: Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.... more

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Product information "Defactinib hydrochloride"

Description: Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK. Which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. Target: FAK. Smiles: Cl.CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1. References: Kang Y, et al. Role of focal adhesion kinase in regulating YB-1-mediated resistance in ovarian cancer. J Natl Cancer Inst. 2013 Oct 2,105(19):1485-95.

Keywords:	VS-6063 hydrochloride, PF 04554878 hydrochloride
Supplier:	TargetMol
Supplier-Nr:	T15092

Properties

Application:	Targets focal adhesion kinase 2 [EC:2.7.10.2] (PTK2B, FAK2)
MW:	546.95 D
Formula:	C20H22ClF3N8O3S

Database Information

CAS :	1073160-26-5\| Matching products
KEGG ID :	K05871 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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