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Defactinib hydrochloride
Defactinib hydrochloride

Item number: TGM-T15092-2mg

Description: Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK. Which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. Target: FAK. Smiles: Cl.CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1. References: Kang Y, et al. Role of focal...
Keywords: VS-6063 hydrochloride, PF 04554878 hydrochloride
Application: Targets focal adhesion kinase 2 [EC:2.7.10.2] (PTK2B, FAK2)
CAS 1073160-26-5
MW: 546.95 D
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