CU-CPT22
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and... more
Product information "CU-CPT22"
Description: CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 µM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41 µM). Target: TLR. Smiles: CCCCCCOC(=O)c1cc(O)c(=O)c2c(O)c(O)c(OC)cc2c1. References: Cheng K, et al. Discovery of small-molecule inhibitors of the TLR1/TLR2 complex. Angew Chem Int Ed Engl. 2012 Dec 3,51(49):12246-9.
| Supplier: | TargetMol |
| Supplier-Nr: | T15020 |
Properties
| Application: | TLR1 antagonist |
| MW: | 362.37 D |
| Formula: | C19H22O7 |
Database Information
| CAS : | 1416324-85-0| Matching products |
| KEGG ID : | K05398 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H334, H410 |
| P Phrases: | P261, P273, P284, P391, P304+P341, P342+P311, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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