43 products were found matching "K05398"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TLR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TLR1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TLR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TLR1. Next,...

TLR 1 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. TLR1 recognizes pathogen-associated molecular pattern with a specificity for gram-positive bacteria. TLR1 has also been designated as CD281. Protein function: Participates in the innate immune...

MMG-11 is an antagonist of the toll-like receptor 1/2 (TLR1/2) heterodimer (IC50 = 0.9 µM in HEK-Blue cells expressing the human receptors). It is selective for TLR1/2 over the TLR2/6 heterodimer (IC50 = 7.4 µM in HEK-Blue cells expressing the human receptors). MMG-11 inhibits TNF-alpha and IL-6 cytokine secretion...

Synthetic. Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response,...

CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2, Ki = 0.41 µM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 (Cay-24126) in RAW 264.7 cells (IC50 = 0.58 µM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as...

CU-T12-9 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer. It is selective for TLR1/2 over the TLR2/6 heterodimer in a secreted alkaline phosphatase (SEAP) assay at concentrations up to 10 µg/ml using HEK-Blue cells expressing human TLR2 and endogenously expressing both TLR1 and TLR6 and anti-TLR...

Formula : C81H156N10O13S.3HCl MW: 1510.3 . 109.4 Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages.Potent and effective immune...

The toll-like receptors (TLRs) in mammals comprise a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Like their counterparts in Drosophila, TLRs signal through adaptor...

Protein function: Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [The UniProt Consortium]

Anti-TLR6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TLR6 from other sources has not been determined. Protein function: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated...