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CU-CPT22
Item number: TGM-T15020-100mg
Description: CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 µM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41 µM). Target: TLR. Smiles:...
| Application: | TLR1 antagonist |
| CAS | 1416324-85-0 |
| MW: | 362.37 D |
From 45.00€
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CU CPT 22
Item number: Cay15244-1
CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2, Ki = 0.41 µM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 (Cay-24126) in RAW 264.7 cells (IC50 = 0.58 µM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as...
| Keywords: | 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid, hexyl ester |
| Application: | TLR1 antagonist |
| CAS | 1416324-85-0 |
| MW: | 362.4 D |
From 78.00€
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