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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-CN2-0048-M500 | 500 mg | - |
3 - 9 business days* |
77.00€
|
|||
AG-CN2-0048-G001 | 1 g | - |
3 - 9 business days* |
132.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Isolated from Colchicum autumnale. Anti-cancer compound - Microtubule assembly inhibitor -... more
Product information "Colchicine"
Isolated from Colchicum autumnale. Anti-cancer compound - Microtubule assembly inhibitor - Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation) - Inhibits mitosis during cell division at metaphase by inhibiting spindle formation - Anti-inflammatory compound - Suppresses monosodium urate crystal-induced NLRP3/NALP3 inflammasome-driven caspase-1 activation, IL-1beta processing and release, and L-selectin expression on neutrophils at micromolar concentrations - Blocks the release of a crystal-derived chemotactic factor from neutrophil lysosomes, blocks neutrophil adhesion to, and inhibits monosodium urate crystal-induced production of superoxide anions from neutrophils at nanomolar concentrations - Drug used in treatment of gout, familial Mediterranean fever, pericarditis and Behect's disease - Investigated for its anti-cancer activity - It has a narrow therapeutic index with no clear-cut distinction between nontoxic, toxic and lethal doses, causing substantial confusion among clinicians - Apoptosis inducer in a variety of normal and tumor cell lines.
Keywords: | NSC 757, EINECS 200-598-5 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-CN2-0048 |
Properties
Application: | Microtubule assembly inhibitor |
MW: | 399,4 D |
Formula: | C22H25NO6 |
Purity: | >98% |
Format: | Solid |
Database Information
CAS : | 64-86-8| Matching products |
KEGG ID : | K07375 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H300, H340 |
P Phrases: | P201, P202, P301+P310, P308+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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