Carfilzomib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the... more
Product information "Carfilzomib"
Description: Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome. Carfilzomib has antitumor activity and may be used to treat multiple myeloma. Target: Proteasome, Autophagy, Apoptosis. Smiles: CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1. References: Kuhn DJ, et al. Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood. 2007 Nov 1,110(9):3281-90.
| Keywords: | PR-171 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1795 |
Properties
| Application: | Targets 20S proteasome subunit beta 5 [EC:3.4.25.1] (PSMB5) |
| MW: | 719.91 D |
| Formula: | C40H57N5O7 |
Database Information
| CAS : | 868540-17-4| Matching products |
| KEGG ID : | K02737 | Matching products |
| Protein Atlas Nr. : | Proteasome and Proteases |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H361, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P321, P302+P352, P305+P351+P338, P308+P313, P332+P313, P337+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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