Azelaprag
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
An APJ agonist, inhibits forskolin-induced cAMP accumulation in CHO cells expressing human APJ... more
Product information "Azelaprag"
An APJ agonist, inhibits forskolin-induced cAMP accumulation in CHO cells expressing human APJ (EC50 = 0.23 nM), increases stroke volume and heart rate and decreases systemic vascular resistance, indicating increased cardiac reserve, in ZSF1 obese rats in a model of diastolic dysfunction at 1 mg/kg, i.v.. SMILES: C[C@H](C1=NC=C(C)C=N1)[C@H](C)S(NC2=NN=C(C3=CN=CC(C)=C3)N2C4=C(C=CC=C4OC)OC)(=O)=O. InChi Code: InChI=1S/C25H29N7O4S/c1-15-10-19(14-26-11-15)24-29-30-25(32(24)22-20(35-5)8-7-9-21(22)36-6)31-37(33,34)18(4)17(3)23-27-12-16(2)13-28-23/h7-14,17-18H,1-6H3,(H,30,31)/t17-,18-/m0/s1. InChi Key: DOMQFIFVDIAOOT-ROUUACIJSA-N
| Keywords: | AMG 986, BGE-105, (alphaS,betaR)-N-[4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl]-alpha,beta,5-trimethyl-2-pyrimidineethanesulfonamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 44644 |
Properties
| Application: | APJ (apelin receptor) agonist |
| MW: | 523.61 D |
| Formula: | C25H29N7O4S |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 2049980-18-7| Matching products |
| KEGG ID : | K04174 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed