Altenusin

Altenusin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay26911-500 500 µg -

6 - 10 business days*

102.00€
Cay26911-1 1 mg -

6 - 10 business days*

182.00€
Cay26911-5 5 mg -

6 - 10 business days*

850.00€
 
Altenusin is a polyphenol fungal metabolite originally isolated from the fungus Alternaria that... more
Product information "Altenusin"
Altenusin is a polyphenol fungal metabolite originally isolated from the fungus Alternaria that has diverse biological activities. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 µM. It is an agonist of the farnesoid X receptor (FXR, EC50 = 3.2 µM) that reduces blood glucose, serum insulin, and serum cholesterol levels, as well as hepatic lipogenic gene expression and steatosis, in a high fat diet-induced mouse model of obesity when administered at 30 mg/kg per day. Altenusin also has antioxidant and antifungal properties.Formal Name: 3,4',5'-trihydroxy-5-methoxy-2'-methyl-[1,1'-biphenyl]-2-carboxylic acid. CAS Number: 31186-12-6. Synonyms: Alutenusin. Molecular Formula: C15H14O6. Formula Weight: 290.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: COC1=CC(C2=C(C)C=C(O)C(O)=C2)=C(C(O)=O)C(O)=C1. InChi Code: InChI=1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20). InChi Key: ADPBTBPPIIKLEH-UHFFFAOYSA-N. Origin: Fungus/Penicillium sp..
Keywords: Alutenusin, 3,4',5'-trihydroxy-5-methoxy-2'-methyl-[1,1'-biphenyl]-2-carboxylic acid
Supplier: Cayman Chemical
Supplier-Nr: 26911

Properties

Application: Bioactive polyphenol fungal metabolite, Src inhibitor
MW: 290.3 D
Formula: C15H14O6
Purity: >98%
Format: Solid

Database Information

CAS : 31186-12-6| Matching products
KEGG ID : K05704 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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