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Altenusin
Item number: TGM-T8895-10mg
Description: Altenusin is a natural nonsteroidal fungal metabolite, as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 µM. Target: FXR. Smiles: C(O)(=O)C1=C(C=C(OC)C=C1O)C2=C(C)C=C(O)C(O)=C2. References: Zheng Z, Zhao Z, Li S, et al. Altenusin, a Nonsteroidal Microbial Metabolite, Attenuates...
| Application: | N-SMase inhibitor |
| CAS | 31186-12-6 |
| MW: | 290.27 D |
From 387.00€
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Altenusin
Item number: Cay26911-1
Altenusin is a polyphenol fungal metabolite originally isolated from the fungus Alternaria that has diverse biological activities. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human...
| Keywords: | Alutenusin, 3,4',5'-trihydroxy-5-methoxy-2'-methyl-[1,1'-biphenyl]-2-carboxylic acid |
| Application: | Bioactive polyphenol fungal metabolite, Src inhibitor |
| CAS | 31186-12-6 |
| MW: | 290.3 D |
From 102.00€
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Altenusin
Item number: AG-CN2-0143-M001
Isolated from Penicillium sp. Antibiotic. Antifungal penicillide. Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor. Strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain...
| Keywords: | MS 341 |
| Application: | N-SMase inhibitor |
| CAS | 31186-12-6 |
| MW: | 290,3 D |
From 165.00€
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