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Item number: Cay26911-1

Altenusin is a polyphenol fungal metabolite originally isolated from the fungus Alternaria that has diverse biological activities. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human...

Keywords:	Alutenusin, 3,4',5'-trihydroxy-5-methoxy-2'-methyl-[1,1'-biphenyl]-2-carboxylic acid
Application:	Bioactive polyphenol fungal metabolite, Src inhibitor
CAS	31186-12-6
MW:	290.3 D

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Altenusin

Item number: AG-CN2-0143-M001

Isolated from Penicillium sp. Antibiotic. Antifungal penicillide. Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor. Strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain...

Keywords:	MS 341
Application:	N-SMase inhibitor
CAS	31186-12-6
MW:	290,3 D

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